The TML is located in room 205 of the Rightmire Hall. The chromatographic and mass spectrometric technology available allows the identification and quantification of known low molecular weight metabolites. Our methods are designed to take advantage of a state-of-the art liquid chromatography (Agilent UHPLC 1290) coupled to a highly sensitive mass spectrometer (AB Sciex QTRAP 5500). Moreover, the laboratory has a High Pressure Liquid Chromatography-Photodiode Array Detector (Waters Alliance HPLC/PDA system) to separate and monitor metabolites that have UV-Vis absorption.
The TML is available for consultation to advise on experimental design, analytical methodologies, and data interpretation. The laboratory operates on a fee-for-service basis. Users with a large volume of samples may be trained to use some of the instrumentation. Please contact Christophe Cocuron.